Diphenhydramine-containing Medicines

Diphenhydramine-containing Medicines

The South African Health Products Regulatory Authority (SAHPRA) wishes to alert healthcare professionals about the risk of serious heart problems, seizures, coma and death associated with the use of high doses of diphenhydramine-containing medicines. An online challenge known as “the Benadryl Challenge” has recently been in the news. Benadryl® is not registered in South Africa (SA), but several products available in SA contain diphenhydramine and may be similarly misused (see SAHPRA website for a list of diphenhydramine-containing medicines).

2020 Nov

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Document Number: DHCPL
Version: 1
Date Updated: 20/11/2020
File Type: pdf
Category: Communication To Health Care Professionals
Unit: Pharmacovigilance